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Also, at the end of season 13 we discovered that Owen's sister Megan is alive despite having been missing for ten years, and Meredith told Nathan Riggs (Martin Henderson) to go to her, like the noble martyr she is. But Megan's return will also have a knock-on effect on her brother Owen, with the guilt over leaving her possibly even bringing his PTSD back.

But showrunner Shonda Rimes has warned that Merthan (Miggs? Other blasts from the past include Teddy Altman, as mentioned above (last seen in season 8), and we haven't seen the last of Jo's abusive husband Dr Stadler (Matthew Morrison), so there's that to look forward to.

After a fire tore through Grey Sloan (formerly Seattle Grace) Hospital at the end of season 13, the place will presumably look a bit different this year.

Jerrika Hinton has left the series, so don't expect to see Stephanie around, and Marika Dominczyk (Eliza) has likewise departed, leaving Jessica Capshaw's Arizona Robbins a singleton.

Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly.

Discontinuation of NSAID therapy is usually followed by recovery to the pretreatment state.

In these patients, administration of an NSAID may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation.

Inform patients of the warning signs and symptoms of hepatotoxicity (e.g., nausea, fatigue, lethargy, diarrhea, pruritus, jaundice, right upper quadrant tenderness, and "flu-like" symptoms).

If clinical signs and symptoms consistent with liver disease develop, or if systemic manifestations occur (e.g., eosinophilia, rash, etc.), discontinue FENORTHO immediately, and perform a clinical evaluation of the patient.

Correct volume status in dehydrated or hypovolemic patients prior to initiating FENORTHO. —Gastritis, peptic ulcer with/without perforation, gastrointestinal hemorrhage, anorexia, flatulence, dry mouth, and blood in the stool.

Monitor renal function in patients with renal or hepatic impairment, heart failure, dehydration, or hypovolemia during use of FENORTHO [ ]. Increases in alkaline phosphatase, LDH, SGOT, jaundice, and cholestatic hepatitis, aphthous ulcerations of the buccal mucosa, metallic taste, and pancreatitis.

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